Antibacterial Resistance, biofilms and infection control: assessment of antibacterial activity of synthetic and natural molecules
Antibacterial-resistant bacteria remain a major global threat and a growing public health concern. In the continuing fight against the hidden ‘pandemic’ antibacterial resistance, the One Health approach is also gradually becoming the most used and encouraged strategy. The aim of this research line is to carry out epidemiological studies to monitor this phenomenon and analyse the trend in the animal ecosystem of domestic, wild, exotic mammals, reptiles and birds, and in their terrestrial and aquatic environment. The microbiota community associated to microplastics, the ESKAPE bacteria and other zoonotic microorganisms are investigated and identified by proteomic science using the mass spectrometry technology (MALDI TOF), they are in-vitro evaluated for biofilm production and monitored about their susceptibility towards synthetic antibiotic and new natural alternative molecules, such as ozone, hemocomponents for non-trasfusional use. Studies of Meta-analysis are carried out as a secondary research tool for evidence-based practice in the health sciences.
Keywords - ENGLISH
Antibiotic resistance, MALDI TOF, Biofilms, Natural molecules, Microplastics, Meta-Analysis, Zoonosis
Active participants in the research line (PI last author or *)
Vincenzo Cuteri; Adolfo Maria Tambella; Giacomo Rossi; Cristina Miceli; Alessandra Roncarati; Livio Galosi; Sandra Pucciarelli; Alberto Vassallo; Anna-Rita Attili
External Collaborations
Massimo Del Fabbro (Università di Milano); Patrizia Nebbia (Università di Torino); Patrizia Robino (Università di Torino); Alessandro Bellato (Università di Torino); Luisa De Martino (Università Federico II di Napoli); Victor Ngu Ngwa (University of Ngaoundere, Cameroon)
Pillar
Animal Health
Macroareas in Animal Health
Diagnostic and therapeutic
Relevant research grants (national/international) funding specifically this Research Line
Fondo di Ateneo per la Ricerca dell’Università di Camerino (FAR 2014-2015); Fondo di Ateneo per la Ricerca dell’Università di Camerino (FAR 2018-2019); Fondo di Ateneo per la Ricerca dell’Università di Camerino (FAR 2019-2020)
Email Address
annarita.attili@unicam.it
Link to Relevant Publications